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yeast_spliceosome — Yeast spliceosome protein interactions (2017)

Description

Weighted network of interactions among the proteins of the spliceosome of the yeast Saccharomyces cerevisiae, as compiled by M. Cantor and collaborators in a study of nestedness across levels of biological organization. Nodes are 103 spliceosome proteins, and an undirected edge connects two proteins with evidence of a physical association between them in the STRING database (2011 version); edges are weighted by STRING's score, the combined reliability of the evidence for the interaction (from 0, no evidence, to 1, strong support), which estimates the probability that the interaction is correct. The network is dense (connectance 0.78). The proteins are not identified in the source data.

The edges have the property weight, the STRING score of the interaction.1


  1. Description obtained in part from the ICON project. ↩

Tags
Biological Protein interactions Weighted
Citation
  • M. Cantor, M. M. Pires, F. M. D. Marquitti, R. L. G. Raimundo, E. Sebastián-González, P. P. Coltri, S. I. Perez, D. R. Barneche, D. Y. C. Brandt, K. Nunes, F. G. Daura-Jorge, S. R. Floeter, P. R. Guimarães Jr., "Nestedness across biological scales." PLoS ONE 12(2), e0171691 (2017) 10.1371/journal.pone.0171691 Sci-Hub
  • D. Szklarczyk, A. Franceschini, M. Kuhn, M. Simonovic, A. Roth, P. Minguez, T. Doerks, M. Stark, J. Muller, P. Bork, L. J. Jensen, C. von Mering, "The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored." Nucleic Acids Research 39, D561-D568 (2011) 10.1093/nar/gkq973 Sci-Hub
Upstream URL OK
https://bitbucket.org/maucantor/unodf_analyses
Networks
Tip: hover over a column header for a description.
Column legend
$\left<k\right>$
Mean degree
$\sigma_k$
Standard deviation of the degrees
$\lambda_h$
Largest eigenvalue of the Hashimoto (non-backtracking) matrix
$\tau$
Random walk mixing time
$r$
Degree assortativity
$c$
Global clustering coefficient
$\oslash$
(Pseudo-) diameter
$S$
Relative size of the largest component
NPs
Node properties
EPs
Edge properties
Name Nodes Edges $\left<k\right>$ $\sigma_k$ $\lambda_h$ $\tau$ $r$ $c$ $\oslash$ $S$ Kind Mode NPs EPs gt GraphML GML csv
yeast_spliceosome 103 4,119 79.98 24.54 86.49 0.62 -0.02 0.94 3 1.00 Undirected Unipartite weight 7 KiB 20 KiB 20 KiB 15 KiB